This morning I got the Nishiki Maricopa out for a 17-mile ride on the Skook. The Selle Anatomica saddle I recently bought is turning out to be one of my best cycling-related purchases. I didn't get any numbness in my danglies during or after the ride.
I think a big part of the comfort is the slot in the middle which provides some pressure relief and improves blood circulation. If you're cycling and experiencing discomfort in your perineum or genitals it's worth looking into getting a better saddle, which doesn't mean one of those big, cushy ones.